Lynn defends her PhD

posted Dec 24, 2016, 2:06 AM by Rod O'Connor

Lynn successfully defended her PhD and gave a very impressive lecture to her thesis committee. A great way to wrap up the 2016 scientific year. Congratulations Dr. Carr!


Another win for Lynn!

posted Jun 27, 2016, 7:09 AM by Rod O'Connor

PhD student Lynn Carr has picked up yet another award for her poster presentation of our research showing, "Super-resolution microscopy reveals microtubule buckling and breaking following nanosecond pulsed electric field exposure in U87 human glioblastoma cells", presented at the 2016 BioEM meeting in Ghent, Belgium. 

The manuscript has now gone off and fingers crossed that the reviewers will appreciate this work as much. The prize money will no doubt be spent on tea and crumpets as she writes up her PhD in the coming months. 



A scientific vacation and superresolution adventure at the Janelia Farm Advanced Imaging Center

posted Sep 10, 2015, 3:51 PM by Rod O'Connor

As France was settling into its summer vacation, PhD student Lynn Carr, Philippe Leveque and Rod O'Connor packed up pulse generators, RF connectors, cells and reagents and jumped on a plane to visit the Advanced Imaging Center of the Janelia Farm Research Campus of the Howard Hughes Medical Institute in Ashburn, Virginia. Two intense weeks of exciting experiments followed at the AIC, which was established in recent years to allow visiting scientists to conduct experiments using the unique instruments developed at Janelia, including imaging systems capable of Interferometric photoactivated localization microscopy (iPALM), Lattice light sheet microscopy,  Single-molecule total internal reflection fluorescence (sm-TIRF) microscopy, Aberration-corrected multifocus microscopy (acMFM), and Live cell multicolor structured illumination microscopy (SIM). We had the pleasure of using the multicolor 3D-SIM scope in standard and TIRF mode, which showed us some of the crispest and most beautiful images of mitochondria and cytoskeleton that we have ever seen. The AIC visiting program was simply fantastic with great staff, support and logistics. We were proud to have been the first team from France to participate in this new program and have a few Terabytes of data to now crunch through. Many thanks to HHMI and the Gordon and Betty Moore Foundation for setting up this great program.
 



Summer conferences 2015

posted Sep 10, 2015, 3:00 PM by Rod O'Connor   [ updated Sep 10, 2015, 3:06 PM ]

It was a great summer conference season for the BioEPIX lab. Within a span of a few days in June our group simultaneously attended conferences on the continent and the west coast of the USA. At the European Conference of Biomedical Optics in Munich, David Moreau was invited to give a platform presentation and awarded runner up prize in the PhD student poster competition; meanwhile Lynn Carr attended BioEM2015 in Asilomar, California, where she picked up 1st prize for her poster. Dr. Sylvia Bardet-Coste picked up a postdoc prize for her presentation and for making a big impact in Monterrey. Two conferences, two continents, triple threat. Our successes followed us home when we made the local news, elevating Lynn to celebrity status in her village when she made the front page of LePopulaire. What a great way to start the summer!

 







Welcome Ryan!

posted Feb 16, 2015, 3:38 PM by Rod O'Connor   [ updated Feb 16, 2015, 3:44 PM ]


Ryan Burke has joined our lab to start his PhD studies after completing a BSc and MSc in Neuroscience with Michael Persinger in Canada. Talk about hitting the ground running -he arrived and was immediately intiated by coil at the hallowed home laboratory of Arsene d'Arsonval in La Porcherie.

Within weeks Ryan is already showing some great results applying ultrashort pulses to cancer cells and visualizing cellular effects with voltage dyes I had on the shelf. Can't wait to see the exciting things we'll do with the new optogenetics tools that have arrived. 

Lab Photo 2015

posted Feb 16, 2015, 12:42 PM by Rod O'Connor   [ updated Feb 16, 2015, 12:54 PM ]



Nice photos of the BioEPIX group 2015 thanks to Claire Darraud. A very hardworking bunch indeed.


Sabrina returns!

posted Feb 6, 2015, 8:32 AM by Rod O'Connor   [ updated Feb 6, 2015, 8:56 AM ]

Sabrina is back for another round of her masters research -this time M2. The blurred pipette says it all as she comes back with a vengence to help us dissect mitochondrial membrane potential changes in cancer cells pulsed by nsPEFs. Welcome back!

Welcome Denise

posted Jan 28, 2015, 3:38 PM by Rod O'Connor   [ updated Feb 2, 2015, 2:43 AM ]

Denise has joined the lab as Ingénieur d'études, bringing her many years of technical experience gained working in Physiology, Development and Neuroscience departments in Cambridge, the Sanger Institute, Janelia Farm HHMI and Roche/ArevaMed. 
The master of precision and repeatability has finally joined the team!

Exciting multiphoton imaging to come in 2014

posted Jan 1, 2014, 5:51 AM by Rod O'Connor   [ updated Jan 1, 2014, 5:52 AM ]

The tuneable femtosecond laser arrived just before Christmas and after some minor optical bricolage our multiphoton imaging system is now functional. An exciting year of intravital in vivo experiments to come in 2014!

Welcome Lynn!

posted Dec 5, 2013, 12:16 PM by Rod O'Connor

Lynn Carr has joined our lab for a PhD, enriching our lab with her existing expertise in biochemistry, proteomics and cell biology.

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