The Oncoelectronics lab (formerly the BioEPIX lab at XLIM) is a  multidisciplinary group in the Bioelectronics (BEL) department at École des Mines de Saint-Étienne in Provence. We are studying the biological effects of
 electromagnetic fields with imaging and biophotonics tools. We are particularly interested in the application of nanosecond pulsed electric fields and intermediate frequency electromagnetic fields for the treatment of cancer. We are also exploring the potential use of ultrashort pulsed electromagnetic fields for stimulating neurons in the brain non-invasively. 
 




The majority of our current research uses live-cell imaging, electrophysiology and molecular tools to investigate the mechanisms mediating the bioeffects of high amplitude, ultrashort pulsed electromagnetic fields. Live-cell imaging allows real-time visualization of dynamic processes in cells and with our microscope-based exposure setups, we can observe the effects of pulsed electromagnetic fields on cell physiology, signalling and morphology in vitro with high temporal and spatial resolution. We routinely make use of established synthetic fluorescent probes for cell physiology and are also exploring the potential of the new generation of genetically-encoded fluorescent protein-based indicators that are becoming available.  We also use multiphoton imaging in our studies of ultrashort pulsed field effects in vivo





We work closely with physicists and engineers in the lab to develop new systems for the generation, delivery and dosimetry of pulsed electromagnetic fields. One of our current goals is to  develop new biophotonics tools for establishing the microdosimetry of electromagnetic fields by the measurement of temperature at the cellular and sub-cellular scale.



Our research philosophy is to tackle multidisciplinary problems at the interface of biology, physics and engineering, and to overcome the arbitrary boundaries set by disciplinary and deparmental structures in science.